7 Best Non-Refrigerated Probiotics (Which is Better?)

The increasing inclination of the general population towards probiotics for disease prevention and cure instead of relying on traditional medication is evident from a recent forecast predicting that the global probiotic market for gut health may increase to 2.1 billion dollars in 2027 from 1.1 billion dollars in 2020.

Hence, manufacturers are constantly upgrading their products, such as making them temperature-resistant to make them more desirable due to their longevity.

Considering this, I’ve compiled a list of the 7 best non-refrigerated probiotics containing an efficacious blend of shelf-stable strains that can help you lose weight, boost immunity, and improve your gut health.

My 4 top picks are:

YourBiology gut+ – Best for both men and women (from personal experience)
Biotics 8 – Best suited for men.
Culturelle Metabolism + Weight Management Capsules – Best For Weight Management
Optibac pregnancy probiotics – Best for pregnant and nursing women.

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How to Pick the Best Non- Refrigerated Probiotics?

Apart from being refrigerated or non-refrigerated, some other factors that you should consider before finalizing your decision are cost, allergens, benefits and disbenefits, dosage form, probiotic strains, and their CFUs.

No Refrigeration Needed

Non-refrigerated probiotics have a reputation for being low maintenance yet extremely effective.

The reason is that they can be feasibly stored and taken anywhere, and they are also less susceptible to losing viable CFUs before reaching your small intestines.

In contrast, refrigerated probiotics are easily perishable, and you can never know if the optimum quantity of viable probiotics was delivered to your gut or not.

Therefore, I will recommend that you prefer non-refrigerated probiotics over refrigerated options because the former indisputably carries greater benefits.

Cost

The more the product has to offer, the higher its cost will be. Hence, refrigerated probiotics are going to cost more than non-refrigerated ones.

The reason behind this is that there are only a limited number of heat-resistant strains of good bacteria, and hence, manufacturers use advanced and patented technologies like MAKKTrek or HPMC capsules to protect the usual strains against environmental stresses.

Therefore, the cheapest option that you may get may cost around $ 20.

Besides that, a larger variety of refrigerated probiotics is available in the range of $30 to $50.

Still, the most expensive yet effective refrigerated probiotics may cost as much as $80.

In the subsequent sections, I have compiled a list of economical, moderately priced, and high-end probiotic pills for you to choose from.

Allergens

If you have any allergies, then it is extremely crucial to look out for potential allergens because they may be manufactured in facilities containing nuts or may have dairy-derived probiotics.

Some examples of ingredients that have the potential to trigger allergic reactions include dairy, eggs, gluten, corn, nuts, shellfish, and peanuts.

In addition, some individuals may prefer non-genetically modified organism (GMO) supplements that do not contain artificial colors, dyes, chemicals, or preservatives.

This product information can greatly influence your decision about buying the product.

Benefits and Disbenefits

You may be investing in a probiotic supplement for imparting a specific health benefit like weight loss or aiding digestion.

Hence, the benefits of the product may also serve as a criterion for your purchase.

It is also wise to overview the potential risk that it may carry and its suitability in different medical conditions or ages because this may also cancel out many options available out there.

For instance, most probiotics are not suitable for children below 14 years of age, while others are specifically formulated for children above 4 years.

Similarly, many probiotics carry risks for pregnant or nursing mothers, while on the other, certain manufacturers have come up with products that have a clear benefit for them.

Dosage Form

Probiotic supplements are available in many different forms, like tablets, capsules, powders, gummies, etc.

Generally, capsules are more effective in delivering viable CFUs to your small intestine, but it may be easier to consume powder or liquid probiotics while traveling.

Therefore, considering the dosage form and instructions on intake will also help you make a better choice.

Probiotic Strains and CFUs

The probiotic strains and their viable CFUs are what make or break the probiotic reputation.

You should essentially look for supplements in which the viable CFUs of good bacteria range between 1 billion CFUs and 10 billion CFUs because supplemental bacteria within this range are known to confer solid benefits.

Additionally, instead of proprietary probiotic blends, products that showcase clinically approved and FDA GRAS probiotic strains should be your preferred choice.

One indication of non-refrigerated probiotics is that it contains spore-forming Bacillus species which are internally resistant to the environment.

In the next section, I have shared my recommendations for some of your individual needs that I hope you’ll find helpful.

7 Best Non- Refrigerated Probiotics

The following list includes different options for men, women, kids, IBS sufferers, weight-conscious individuals, pregnant women, and for supporting immune function.

1. YourBiology Gut + (Best For Women & Men)

CFU: 40 billion CFUs

Dosage: You must take two capsules daily, one in the morning and the other before bed.

Probiotics Strains: 4 species

3 Lactobacillus species (L. acidophilus, L. Plantarum, L. Paracasei)
1 Bifidobacterium specie (B. Lactis)

Form/Type: capsule

Certifications: It is manufactured in cGMP-certified facilities.

Storage: It is shelf-stable and does not require refrigeration.

Cost: One bottle contains 60 capsules that will last 30 days and will usually cost you $79.99.

The best part about the YourBiology Gut + probiotic is that each capsule delivers the exact CFU of the viable bacteria to the gut as is mentioned on the label.

Here is an overview of how Your biology gut + improves women’s health and remains shelf stable.

The Probiotics Are Protected By MAKTrek Technology: The manufacturers employ the cutting-edge MAKTrek bipass technology that encapsulates the probiotics in algal polysaccharides, which protects them from stomach acid and delivers them directly to the intestines.

Improves Women’s Overall Well-Being: Apart from that, this supplement contains the scientifically acclaimed Lactobacillus species and the FDA GRAS Bifidobacterium lactis strain that are beneficial in re-establishing a healthy vaginal microflora, combating the symptoms of IBS, regulating bowel movements and SIBO, improving skin texture, weight management, immunity, and cognitive health.

Optimizes Gut Functioning: Additionally, it contains the fructooligosaccharide fiber, which nourishes the existing gut commensals while simultaneously supporting the colonization of the good supplemental bacteria.

Lastly, the prebiotic fiber also aids glucose metabolism and promotes bowel regularity.

Pros:

Improves feminine health, immunity, weight loss, and gut health.
Vegan, non-GMO, allergen (dairy, soy, gluten), and preservatives free.
Does not require refrigeration.
The MAKTrek technology enables 250 times better survival and absorption of the
Manufactured in cGMP-registered facilities.
60-day money-back guarantee and free delivery.
Contains prebiotic fiber.

Cons:

Not recommended for ages below 18 years and pregnant or nursing women.
Cannot be bought from other online or physical stores.
May cause side effects like stomach upset and gas.

Where to buy:

You can order a bundle or a single bottle from only the official website here.
As mentioned above, the non-discounted price of a single bottle is $79.99.
Whereas you can purchase a bundle of 3 bottles for $239.97 and 5 bottles for $399.95.

2. Biotics 8 Probiotics (Best For Men)

CFU: 20 billion CFUs

Dosage: You have to consume its 3 capsules every morning.

Probiotics Strains: 10 species

7 Lactobacillus species (L. casei, L. paracasei, L. plantarum, L. fermentum, L. longum, L. acidophilus, L. rhamnosus)
1 yeast specie (Saccharomyces cerevisiae)
2 Bifidobacterium species (B. longum, B. breve)

Form/Type: capsule

Certifications: It is produced in cGMP-certified facilities.

Storage: It does not require refrigeration and is shelf stable.

Cost: You can buy a one-month supply (90 capsules) of Biotics 8 at a retail price of $79.99.

The Biotics 8 probiotic stands out from its counterparts because it contains digestive enzymes that prevent stomach issues and aids digestion.

Here is why Biotics 8 probiotic pills stand out from their counterparts and are protected from environmental stresses.

The HPMC Technology Ensures Optimal Delivery Of The Probiotic Strains: Moreover, the manufacturers make use of the HPMC technology that makes the pill-resistant to dissolution in the stomach acid and safely treks it to the intestines.

It is worth mentioning that HPMC capsules are stronger than conventional gelatin capsules.

Prevents Gastrointestinal Side Effects: The digestive enzymes, namely protease, amylase, and lipase, help to break down the macronutrients, which cut the problem of indigestion by the root.

Additionally, it prevents the development of gastrointestinal problems like bloating, diarrhea, or nausea, which are common with other probiotic supplements.

The mechanism that works behind this is that the supplemental bacteria in probiotic supplements may initially over-populate the gut.

These bacteria then rush to digest the food which releases gas as a by-product and may cause gastrointestinal side effects.

Boosts Men’s Overall Health: This product contains probiotics with proven effectiveness in improving testosterone levels, IBS symptoms, fat loss, mental well-being, and digestion.

What is more, is that the Biotics 8 supplement specifically caters the men’s needs, not just with the probiotics but also with added vitamin D, which supports male fertility and muscle development.

Normalizes Gut Function: It also has prebiotic fiber derived from chicory root and inulin, which will feed the gut-friendly bacteria while simultaneously regulating blood sugar levels and bowel movements.